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 Speaker Profile

PMWC LUMINARY AWARD
Co-founded Kite; led Yescarta—the first adult CD19 CAR-T

M.D., Executive Chairman & Co-Founder, Allogene Tx

Biography
Arie S. Belldegrun is a trail‑blazing urologic‑oncologist‑turned‑biotech entrepreneur whose company‑building spree—from Agensys and Cougar to Kite Pharma—helped usher in the first FDA‑approved CAR‑T therapy and led to Kite’s $11.9 billion sale to Gilead Sciences. After that landmark exit, he co‑founded Allogene Therapeutics and still serves as its Executive Chairman, steering the next wave of off‑the‑shelf (allogeneic) CAR‑T cell products toward the clinic. Beyond Allogene, Belldegrun deploys capital through Bellco Capital, Two River, Symbiotic Capital, Vida Ventures, and the real‑estate venture Breakthrough Properties, nurturing a constellation of startups that translate science into patient impact. Over three decades on UCLA’s faculty, he has authored 500‑plus scientific papers, mentored a generation of physician‑scientists, and kept patient benefit at the center of every deal—cementing his reputation as one of precision medicine’s most influential builders.


 Session Abstract – PMWC 2026 Silicon Valley

Track 1: Next-Gen Tx - March 4 9.00 A.M.-5.00 P.M.


Track Chair:
Priti Hegde, Kite Pharma

PMWC Award Ceremony
• Michel Sadelain, Columbia University
• Arie S. Belldegrun, Allogene Therapeutics

Keynote: Engineering the Future: Innovations in CAR-T Therapy Design
• Michel Sadelain, Columbia University

Keynote: The Industrialization of Cell Therapy:From Autologous Pioneers to Allogeneic Frontiers
• Arie S. Belldegrun, Allogene Therapeutics

Next Generation CAR-T Cell Therapies: Expanding Targets and Enhancing Designs
• Chair: David Barrett, Kite Pharma
• Carl June, University of Pennsylvania
• Michel Sadelain, Columbia University

Tumor-Infiltrating Lymphocytes (TILs): Advances and Challenges in Solid Tumors
• Chair: Allison Betof Warner, Stanford University
• George Coukos, Ludwig Institute for Cancer Research
• Max Julve, Stanford
• Stephanie Goff, NIH/NCI

Allogeneic & In Vivo Cell Therapies: Manufacturing & Clinical Progress
• Chair: Arie S. Belldegrun, Allogene Therapeutics
• Zach Roberts, Allogene Therapeutics
• Adrian Bot, Capstan Therapeutics
• Aliya Omer, AstraZeneca
• Priti Hegde, Kite Pharma

Smart Scaling: Leverating AI & Automation to De-Risk Advanced Therapy Manufacturing
• Chair: Stacie Calad-Thomson
• Samuel Rodriques, FutureHouse
• Manuel Leonetti, Biohub
• Fabian Gerlinghaus, Cellares

Designing Automated Platforms for Scalable Cell Therapy Manufacturing
• Fabian Gerlinghaus, Cellares

In-Vivo Myeloid Programming: Engineering the Innate Immune System for Solid Tumor Therapy
• Daniel Getts, Myloid Therapeutics

Operationalizing Cell & Gene Therapy Trials in a Large Health System
•Snehit Prabhu, Stanford

Gene Editing & Synthetic Biology for Therapy
• Chair: Trevor Martin, Mammoth Biosciences
• Ken Drazan, ArsenalBio
• Lynn Seely, Lyell
• Kole T. Roybal, Parker Institute
• David Kirn, 4DMT

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