Speaker Profile
M.D.,Ph.D., Partner, RA Capital
Biography
Most recently, Adrian Bot, M.D., Ph.D. was the founding Chief Scientific Officer and Executive Vice President of Research and Development at Capstan Therapeutics, an Abbvie company developing next generation precision medicines with focus on in vivo CAR engineering. Previously, he held leadership roles at Kite Pharma and Kite, a Gilead Company, including Chief Scientific Officer and Vice President of Translational Medicine and Discovery Research, respectively. At Kite, he contributed to the development of first-in-class CAR T cell therapy products for cancer. Dr. Bot also served in various senior R&D leadership positions at MannKind Corp and Alliance Pharmaceutical Corp, La Jolla, California. He obtained his M.D. in Romania in 1993, his Ph.D. in Biomedical Sciences at Mount Sinai School of Medicine in New York in 1998 and subsequently, he was a Guest Scientist at the Scripps Research Institute in La Jolla, California.
Session Abstract – PMWC 2027 Silicon Valley
Track Chair:
Mark Genovese, Eli Lilly
PMWC Award Ceremony
• Miriam Merad, Mount Sinai (Luminary)
• Jeffrey A. Bluestone, UCSF (Luminary)
Featured Speakers
• Miriam Merad, Mount Sinai
• Jeffrey A. Bluestone, UCSF
• Gallia Levy, Gilead
• Marcela V. Maus, Harvard
• Nick Wilson, Biogen
• Megan Levings, BC Children's Hospital Research Institute
• Min Bao, Kali Therapeutics
• Purvesh Khatri, Stanford
• Heleen Scheerens, Genentech
• Pascal Geldsetzer, Stanford
• Dan Littman, NYU
• Anne Kasmar, Parexel
Macrophages Across Inflammation, Cancer & Aging
Master regulators of tissue health and disease across precision immunology.
Immune Reset in Autoimmune Disease
CAR-T, in vivo CAR, and the pursuit of durable remission.
Beyond Broad Immunosuppression
Tolerance, Tregs, and disease-modifying approaches.
Turning Biomarkers on Their Head
What we can measure before we can reliably predict response.
Precision Immunology in Clinical Development
Trial enrichment, deeper endpoints, response prediction, and regulatory strategy.
The Microbial Roots of Autoimmunity
Chronic infection, dysbiosis, and microbial signals shaping disease.
PMWC Hall of Impact
Previous Speakers Include
Nobel laureates, technology founders, regulators, CEOs and scientific pioneers who have taken the PMWC stage.
