In a world grappling with a surge in chronic diseases, our approach to healthcare is evolving. The traditional model, addressing patients post-illness, is costly and lacks individualization. The existing medical care model frequently focuses on individuals only after they transition into patients, leading to elevated costs linked to treating chronic and advanced-stage illnesses. There is an emerging requirement for an interdisciplinary strategy to comprehend and manage diseases.

Next month’s PMWC January 24-26, 2024 Silicon Valley will cover structural variations (SV) which are the epicenter of change, exploring the synergy of multi-omics, AI, and precision health. The challenge in using advanced sequencing methods lies in relying on past databases for specific genetic variations. While this works well for some variations, it becomes complicated for SVs impacting certain traits, as only a fraction has been cataloged. This poses a challenge for clinicians dealing with patients exhibiting never-before-seen mutations. An exciting solution emerging is the use of multi-omics, providing additional confirmation to genomic theories. The integration of AI is poised to take this trend to the next level, promising further advancements in genetic understanding.

“Multi-omics & AI together have the potential to significantly accelerate the widespread use of ‘omics data in healthcare”, says Steve Turner, Founder of PacBio. He anticipates a transformative impact, merging multi-omics and AI for data interpretation. 2023’s rapid changes set the stage, with biology poised for a breakthrough akin to Large Language Models (LLMs).

Precision health is on the rise, driven by advancements in omics technologies and computational capabilities. Overcoming sequencing hurdles is crucial, and the exciting trend of using multi-omics for confirmation is gaining momentum. Turner states, “I am very excited as I am seeing two important trends that, both individually and together, are going to have a big impact in the next few years. I am talking about multi-omics and AI to help with the interpretation of all the data we have been – will continue – producing.”

Turner’s anticipation for PMWC 2024 Silicon Valley is fueled by the prospect of witnessing industry responses to transformative shifts, foreseeing AI tools predicting novel variant effects and ushering in a new healthcare era. He emphasizes the event’s significance, eager to learn how government and industry players are adapting to these changes. Next month’s PMWC conference promises to be thrilling, setting the stage for groundbreaking advancements and discussions.

Don’t miss the opportunity to shape the future of healthcare at PMWC January 24-26, 2024—a pivotal conference uniting experts, thought leaders and innovators to define the next era in healthcare through the intersections of multi-omics, AI, and precision health.

Key players are contributing to the program representing the various technological advancements and applications:
•    New Frontiers in Genomic Analysis & Interpretation – a panel discussion with Robert Sebra (ISMMS), Anshul Kundaje (Stanford University), Chaz Langelier (UCSF) and Orly Alter (Prism AI)
•    From Potential to Reality: Bringing Nanopore Sequencing to Clinical Practice – a panel discussion chaired by Emma Stanton (Oxford Nanopore) with Charles Chiu (UCSF)
•    Population Sequencing at Scale: Impact and Future Path of Genomic Programs – a panel discussion chaired by Stacey Gabriel (Broad Institute) with Heidi Rehm (MGH), Cindy Lawley (Olink), and John Gaziano (Million Veterans Program [MVP])
•    The Economic Perspective on Genomics – a panel discussion chaired by Bill Hyun (UCSF), Walter Kowtoniuk (Third Rock Ventures), Steve Turner (PacBio), Kandaswamy Vijayan (Zafrens) and Vishal Gulati (Recode Health Ventures)
•    NCI Showcase with Xiaofeng Xie (MicrOmics Technologies)
•    PMWC Showcase: Tara Crawford Parks (DNA Genotek), Varun Dwaraka (TruDiagnostic), John Butler (Quantumcyte, Inc), Paul Spellman (UCLA), Solomon Endlich (Base5 Genomics), Ramin Khaksar (Clear Labs)
•    Building Bridges: Precision Medicine Communities a talk by Kumar Prashant (Karkinos)

Register now before the rate goes up significantly.

Sincerely,
Tal Behar

President & Co-founder, PMWC
PMWC 2024 Silicon Valley – January 24-26, 2024

The Precision Medicine World Conference (PMWC)

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