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Interview Questions for Ed Kim, City of Hope

Interview with Track Chair: Edward S. Kim, MD, City of Hope

Interview with PMWC 2026 Track Chair: Edward S. Kim, MD, City of Hope

Responses to interview questions from Tal Behar, Precision Medicine World Conference

Edward S. Kim, MD, Vice Physician-in-Chief, City of Hope National Medical Center; System Director, Clinical Trials, City of Hope

Track Chair: Systems Integration & Variant Interpretation
Topic: A national clinical trials model that expands access and accelerates enrollment

PMWC 2026 Track Chair Systems Integration & Variant Interpretation
View the Full PMWC 2026 Program

1

The Model: One Hub, Many Sites

City of Hope’s approach is built around a centralized operational hub that can activate and run trials across a distributed, national footprint.

Q1 What’s the innovation in your national clinical trials model?
A: One centralized hub supports multiple research locations across the U.S., so we can open a trial in multiple states simultaneously and manage operations from a single team.
Q2 What changes operationally vs. traditional models?
A: Traditional models are site by site and slow. Ours is a distributed, digitally connected network with centralized activation, oversight, and support, built to scale rapidly without overhauling core systems.

2

Why Patients Care: Access That Reaches Them

Speed matters, but access matters more. The network is designed to bring trial options closer to home, especially for communities that are typically left out.

Q3 Why does this matter for patients?
A: It expands access to emerging, life saving treatments closer to home, especially for communities that typically don’t have trial options.
Q4 What’s the “North Star”?
A: “Offer all our patients, regardless of where they live, the opportunity to participate in clinical trials”, bringing promising options earlier than standard care.

3

Speed, Scale, and What Runs on the Network

Centralization is not just organizational, it changes the timeline: activation, enrollment, and execution can move faster across a wide geographic footprint.

Q5 How does this affect enrollment speed and volume?
A: The operational efficiency of the centralized model reduces time to first patient, increases enrollment, and keeps trials moving across a wide geographic footprint.
Q6 What kinds of studies run on this network?
A: NIH sponsored, industry sponsored, and investigator initiated trials, including City of Hope developed investigational medicines.

4

Consistency, Differentiation, and What’s Next

A national footprint only works if quality is consistent. This model is built to standardize execution while expanding reach and portfolio breadth.

Q7 How do you keep quality and expertise consistent nationwide?
A: The hub provides centralized processes and clinical decision making expertise to all sites, so protocol execution and patient management are standardized.
Q8 What’s your differentiator among academic centers?
A: We’re the first academic center with a national clinical trial network paired to a large, diverse patient population, a combination that enables unprecedented access and scalable operations.
Q9 What’s next for the model?
A: Continued network expansion and portfolio growth, so investigators can bring groundbreaking science to every City of Hope location without sacrificing speed or quality.
Q10 One line takeaway for sponsors and investigators
A: If you need multi state activation, faster enrollment, and consistent execution, a centralized hub national network is the shortest path.
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