See the PMWC 2026 Speakers
Nobel Laureate
Founder & CEO
Nobel Laureate
FDA Commissioner
Select Speakers:
PMWC 2026 LUMINARY HONOREE
Co-founder & President of OpenAI
Co-founder & President of OpenAI
PMWC 2026 PIONEER HONOREE
Ranked #2 Most Influential Person in Healthcare in 2024
PMWC 2026 SPEAKER
UNEP Entrepreneurial Vision Laureate
PMWC 2026 PIONEER HONOREE
*Nobel Laureate
PMWC 2026 LUMINARY HONOREE
Co-founder & Co-CEO of Chan Zuckerberg Institute
PMWC 2026 SPEAKER
President & CEO of Stanford Health Care
President & CEO of Stanford Health Care
March 4-6 Silicon Valley Program:
From Code to Cure
Day 1 — March 4
9:00 AM – 5:00 PM
Day 1: Track 1 — Engineered Cell-Based Next-Gen Therapies
Next-Gen Therapies Track
Track Chair: Cindy Perettie, Kite Pharma
PMWC Award Ceremony
- Michel Sadelain, Columbia
- Arie S. Belldegrun, Allogene Therapeutics
Keynote
Engineering the Future: Innovations in CAR-T Therapy Design
- Michel Sadelain, Columbia
CAR-T Cell Therapies: Strategies in Mitigating Challenges in Solid Tumor Delivery
- Chair: David Barrett, Kite
- Carl June, University of Pennsylvania
- Michel Sadelain, Columbia
Tumor-Infiltrating Lymphocytes (TILs): Advances and Challenges in Solid Tumors
- Chair: Allison Betof Warner, Stanford
- George Coukos, Ludwig Institute for Cancer Research
- Max Julve, Royal Marsden
- Stephanie Goff, NIH/NCI
Allogeneic & In Vivo Cell Therapies: Manufacturing & Clinical Progress
- Chair: Arie S. Belldegrun, Allogene Therapeutics
- David Chang, Allogene Therapeutics
- Adrian Bot, Capstan Therapeutics
- Aliya Omer, AstraZeneca
- Priti Hegde, Kite Pharma
Designing Automated Platforms for Scalable Cell Therapy Manufacturing
- Fabian Gerlinghaus, Cellares
TCR-Based Cell Therapies: New Targets and Clinical Advances
- Chair: Diwakar Davar, UPMC
- Lauren Harshman, Clasp Therapeutics
- Cassian Yee, MD Anderson
Gene Editing & Synthetic Biology for Therapy
- Chair: Matthew Porteus, Stanford
- Rachel Haurwitz, Caribou Biosciences
- Kole T. Roybal, Parker Institute
- Ken Drazan, ArsenalBio
Synthetic Circuits for Smarter Cell Therapies: Enhancing NK Precision and Persistence
- Gudrun Stengel, Alida BioSciences
Day 1: Track 2 — AI in Imaging & Predictive Simulation
AI & Computational Medicine Track
Track Chair: Sharat Israni, UCSF
PMWC Award Ceremony Honorees
- Regina Barzilay, MIT
- Joe Petro, Microsoft (Dragon)
- Curtis P Langlotz, Stanford
Scaling AI from Radiology to the Entire Health System
- Joe Petro, Microsoft
Core AI Methods for Precision Medicine Foundation
- Regina Barzilay, MIT
- Joe Petro, Microsoft
- Curtis P Langlotz, Stanford
Core AI Methods for Precision Medicine Foundation
- Chair: Sharat Israni, UCSF
- James Zou, Stanford
- Regina Barzilay, MIT
- Olivier Gevaert, Stanford
Foundation & Multimodal Models in Precision Medicine
AI-Enhanced Imaging: Radiomics, Radiogenomics & Simulation
- Chair: Chris Hare, Canon Medical
- Ángel Alberich-Bayarri, Quibim
Translational Data Science for Drug Development & Precision Trials
- Chair: Janusz Dutkowski, Data4Cure
AI Digital Twins & Predictive Simulations in Healthcare
Contrast-Free MRI and Low-Dose CT: AI as a Safety Enabler
Clinical Workflow Integration & Decision Support in Imaging
Digital Twins & Predictive Simulation for Therapy Planning
Generative Models for Image Reconstruction & Denoising
Uncertainty & Explainability in Imaging AI for Clinical Adoption
Edge AI for Real-Time Imaging in Scanner & OR Workflows
Multimodal Fusion: Imaging + Omics + EHR for Outcome Prediction
Day 1: Track 3 — Liquid Biopsy – Early Detect. & Screening
Precision Diagnostics Track
Track Chair: Victor Velculescu, Johns Hopkins
PMWC Award Ceremony
- Pioneer Honoree: Klaus Pantel, UKE & ELBS
- Pioneer Honoree: Daniel De Carvalho, University of Toronto
- Luminary Rebecca Fitzgerald, University of Cambridge
Keynote
- Klaus Pantel, UKE & ELBS
Advancing Minimal Residual Disease (MRD) Detection through cfDNA and cfRNA Profiling
- Chair: Luis Diaz, MSKCC
- Anne-Renee Hartman, Adela
Early Cancer Detection / Regulatory / Population Health
- Peter Bach, DELFI Diagnostics
- Joshua J. Ofman, GRAIL
Role of AI in Liquid Biopsies and Cancer Detection
- Chair: Amoolya Singh, DELFI Diagnostics
Clinical Utility of Fragmentomics for Early Cancer Detection
cfDNA Methylation Signatures: From Bench to Clinical Deployment
Exosomes and Extracellular Vesicles: Expanding the Liquid Biopsy Toolbox
Multi-Cancer Early Detection: Defining Value and Managing False Positives
Population-Scale Screening: Designing Trials for Real-World Impact
Integration of Liquid Biopsy with Imaging and Traditional Screening Modalities
Regulatory and Reimbursement Pathways for Early Detection Assays
Standardization of Sample Collection and Pre-Analytical Variables
Beyond Oncology: Liquid Biopsy Applications in Transplant and Infectious Disease
Single-Cell Approaches to Circulating Tumor Analysis
Day 1: Track 4 — Systems Integration & Variant Interpretation
Integrated Precision Medicine Track
PMWC Award Ceremony Honorees
- Mark Daly, Broad Institute
- Gordon Sanghera, Oxford Nanopore
- Howard J. Jacob, Abbvie
The Data Factory: Building Systems to Integrate Millions of Genomes for Variant Interpretation
- Chair: Stephen B. Montgomery, Stanford
- Carlos D. Bustamante, University of Oklahoma
- Mark Daly, Broad Institute/FinnGen
- Manuel Rivas, Stanford
- Mark McCarthy, Genentech
- Nilah Ioannidis, UC Berkeley
Biobanks to Bedside: Cutting VUS in Cancer, Cardio & Rare—What’s Working Now
- Chair: Ben Neale, Broad Institute
- Daniel MacArthur, CPG/Genomes/gnomAD
Beyond the Read: Integrating Long-Read Data into the Clinical Variant Pipeline
- Chair: Gordon Sanghera, Oxford Nanopore Technologies
- Hanlee P. Ji, Stanford
DNA to FDA: How Genetic Targets Win Labels & Coverage
- Chair: Razelle Kurzrock, Medical College of Wisconsin
- Russ B Altman, Stanford
Common Diseases in Clinical Cohorts – Not Always What They Seem
- Howard J. Jacob, Abbvie
25+ Years of the Human Genome — What Made It to the Bedside
- Chair: Ralph Snyderman, Duke
- J. Craig Venter, Craig Venter Institute (JCVI)
- Brook Byers, KPCB
- Lee Hood, Phenome Health
Day 2 — March 5
9:00 AM – 5:00 PM
Day 2: Track 1 — Immunotherapies & Targeted Therapies
Next-Gen Therapies Track
Track Chair: Ira Mellman, Medici Therapeutics
PMWC Award Ceremony
- Jedd D. Wolchok, Weill Cornell Medicine
- Suzanne Topalian, Johns Hopkins
- Levi Garraway, Roche
Targeting the Tumor Microenvironment (TME) in Practice: Biomarkers & Combos
- Chair: Ira Mellman, Medici Therapeutics
- Dmitry Gabrilovich, AstraZeneca
Immunotherapy with Personalized Cancer Vaccines: Who, When, How Fast?
- Chair: Suzanne Topalian, Johns Hopkins
- Tal Zaks, Orbimed
- Lelia Delamarre, Genentech
ADCs in the Checkpoint Era: Who Benefits, What to Combine, What to Avoid
- Chair: Shreya Badhrinarayanan, Pfizer
- S. Peter Kang, Daiichi Sankyo
Strategic IP Management in Cell and Gene Therapy: Navigating Legal and Practical Challenges
- Janet Xiao, Morrison & Foerster LLP
Checkpoint 2.0 in Practice: PD-1+VEGF Wins, Resistance Salvage & Biomarker Gates
- Chair: Jedd D. Wolchok, Weill Cornell Medicine
Future Breakthroughs in Immuno-Oncology: New Targets, Modalities & Biomarker Decision Gates
- Chair: Levi Garraway, Roche
Day 2: Track 2 — AI in Clinical Decision Support & RWE
AI & Computational Medicine Track
Track Chairs: William Oh, Yale & David Reese, Amgen
PMWC Award Ceremony Honorees
- Nigam Shah, Stanford
Keynote
- David Reese, Amgen
Keynote
- Zachary Ziegler, OpenEvidence
Real-World Evidence & Clinical AI: Closing the Loop Between Data and Care
- Chair: Roxana Daneshjou, Stanford
- Aashima Gupta, Google
- David Sontag, Layer Health
- Brigham Hyde, Atropos Health
- Brian Bradbury, Amgen
From Data to Decisions: Building Regulatory-Grade RWE from EHR Systems in Oncology
- Chair: Kate Estep, Flatiron Health
AI for Clinical Decision Support: From Models to Bedside
- Chair: Amrita Basu, UCSF
- Anurang Revri, Stanford
- Emily Alsentzer, Stanford
- Okan Ekinci, Roche
Operationalizing AI in Health Systems: Trust, Adoption & Outcomes
- Chair: Danton Samuel Char, Stanford
- Matthew Solomon, Sutter Health
- Karan Singhal, Head of Health, OpenAI
- Sina Bari, iMerit Technology
- Hal Paz, Khosla Ventures
Safe, Scalable AI in Clinical Practice: What’s Working and What’s Not
- David Entwistle, CEO, Stanford Health Care
Workflow-First Clinical AI: Integration Patterns, Guardrails & Change Management
- Jorge Duran, Klick Health
From Patient-Generated Data to Regulatory-Grade RWE: Design, Bias & Outcome Linkage
- Greg Bowyer, Evidation
Day 2: Track 3 — Liquid Biopsy – Therapy Guidance & Monitor
Precision Diagnostics Track
Track Chair: Adrian Lee, University of Pittsburgh
PMWC Award Ceremony Honorees
- Dennis J. Slamon, UCLA
Neoadjuvant to Adjuvant MRD: How Early Is Early Enough?
- Chair: Angela DeMichele, UPenn
- Halla Nimeiri, Tempus
- Aparna Parikh, Harvard
- Minetta Liu, Natera
Serial ctDNA-Guided Therapy Switching (SERENA-6 & Beyond)
- Chair: Pedram Razavi, MSK
Multi-Omics Monitoring Beyond Variants: Methylation, Fragmentomics, EV/ctRNA
- David T. Miyamoto, Massachusetts General Hospital
- Maximilian Diehn, Stanford
From Validation to Payment: Coverage Pathways That Work
- Mark Stewart, Friends of Cancer Research
- Hilary Gee Goeckner, American Cancer Society (ACS)
- Sally Werner, Cancer Support Community
- Gabriel A. Bien-Willner, Palmetto GBA
MRD for IO & Cell Therapy: Dynamics that Predict Response
ctDNA + Imaging + Clinical Markers: Integrated Response Algorithms
Chasing 10⁻⁵: Optimizing MRD Assays for Solid Tumors
ctDNA + Imaging + Clinical Markers: Integrated Response Algorithms
Chasing 10⁻⁵: Optimizing MRD Assays for Solid Tumors
Tumor-Informed vs Tumor-Agnostic MRD: Showdown with Data
Rapid MRD to Decision: Logistics That Cut Days to Action
Harmonizing MRD: Reference Standards, Proficiency & Cross-Lab Concordance
Below the Noise Floor: Low-VAF Calling, Error Suppression & QC
Clinical Utility & Coverage: Evidence That Moves Payers on MRD
Rapid MRD to Decision: Logistics That Cut Days to Action
Harmonizing MRD: Reference Standards, Proficiency & Cross-Lab Concordance
Below the Noise Floor: Low-VAF Calling, Error Suppression & QC
Clinical Utility & Coverage: Evidence That Moves Payers on MRD
Day 2: Track 4 — Integration & Implementation of Precision Medicine
Integrated Precision Medicine Track
Track Chair: Burns Blaxall
PMWC Award Ceremony Honorees
- Euan Ashley, Stanford
- Jeff Balser, VUMC
Keynote
- Lee Hood, Phenome Health
Precision Medicine at Scale, Lessons from Vanderbilt
- Jeffrey R. Balser, Vanderbilt
Clinical Genome Interpretation / Hospital-Level Programs
- Euan Ashley, Stanford
Current State of Precision Medicine Implementation
- Chair: Susanne Munksted, Diaceutics
Keys to Successful Implementation of a Precision Medicine Program
- Chair: Howard McLeod, GeneDx
- David E. Lanfear, Henry Ford Health
- Kevan Simms, Ochsner Health
From $/Gb to Outcomes: Simplifying Genomics for Health Systems
- Fireside Chat: Jacob Thaysen, CEO, Illumina
Key Players in Successful Implementation – Beyond Oncology
- Chair: Damon Hostin, Illumina
- Shaista Malik, UC Irvine
Precision Medicine at Scale: Lessons from a Statewide Genomic Initiative
- Chair: Premal Shah, MyOme
Achieving Comprehensive Precision Medicine
- Chair: Burns Blaxall
- Trish Brown, GeneDx
- Sarah Hersey, BMS
- Euan Ashley, Stanford
Making PM Work: FHIR/OMOP Patterns That Survive Production
Consent, Identity & Data Rights: Trust Infrastructure for PM
Consent, Identity & Data Rights: Trust Infrastructure for PM
Day 3 — March 6
9:00 AM – 4:00 PM
Day 3: Track 1 — RNA, Stem Cell and Gene-Based Therapies
Next-Gen Therapies Track
Track Chair: Catriona Jamieson, UCSD
PMWC Award Ceremony Honorees
- Judy Faulkner, Epic
- Svetlana Mojsov, The Rockefeller University (GLP-1)
- Alexis C. Komor, UCSD
Opening Talk
- Catriona Jamieson, UC San Diego
GLP-1: From Hormone Discovery to a Global Therapeutic Revolution
- Svetlana Mojsov, The Rockefeller University
What’s Next at Epic?
- Peter DeVault, Epic
Modified mRNA, siRNA, ASOs
- Chair: Alexis C. Komor, UC San Diego
- Niren Murthy, UC Berkeley
- Gene Yeo, UC San Diego
- Reuben Harris, UT Health San Antonio
Stem Cell–Targeted Therapeutics: Small Molecules & Biologics
- Chair: Catriona Jamieson, UC San Diego
- Irving L. Weissman, Stanford
In Vivo Gene Therapies
- Chair: Gene Yeo, UC San Diego
- Mark A. Kay, Stanford
- David Schaffer, UC Berkeley
Diagnostics, Prognostics, and Patient Stratification
- Chair: Ezra Cohen, Tempus
- Eitan Ruppin, NIH
- Danielle Hamel, Tempus
- David Ledbetter, Florida State University
- Ludmil Alexandrov, UC San Diego
Closing
- Catriona Jamieson, UC San Diego
Day 3: Track 2 — AI in Drug Discovery & Computational Bio.
AI & Computational Medicine Track
Track Chairs: Gad Getz, Broad Institute & Alex Morgan, Khosla Ventures
PMWC Award Ceremony Honoree
- Greg Brockman, President & Co-Founder, OpenAI
- Steve Wozniak, Co-Founder, Apple
Fireside Chat
- Vinod Khosla, Khosla Ventures
- Greg Brockman, President & Co-Founder, OpenAI
Target Discovery: Beyond Genomics – Revealing Hidden Layers of Biology with AI
- Keynote: Stephen Quake, CZ Biohub
- Aritro Nath, City of Hope
- Massa Shoura, Phinomics
- Omar Serang, DNAnexus
Illuminating Drug Discovery: AI Models That Learn From Biology
- Erwin Estigarribia, HEADLAMP Health
Harmonizing the Data Economy: Enabling AI Across Institutions and Therapeutic Areas
- Noah Nasser, Datma
Can AI Really Create the Next Blockbuster Drug?
- James Zou, Stanford
Interpretable AI for Biomarker Discovery: Accelerating Drug Development
- Chair: Rajat Roy, PATHOMIQ INC
Closing the Loop: AI in the Messy Middle of Drug Development
- Ari Caroline, Weave Bio
- Dina Katabi, Emerald / MIT
Is AI the New Drug?
- Michael J. Kahana, Nia Therapeutics
Generative AI for Novel Molecular Design: Hype vs. Translational Reality
Day 3: Track 3 — Spatial Biology & Single-Cell Multi-Omics
Precision Diagnostics Track
Track Chair: Christina Curtis, Stanford
PMWC Award Ceremony Honoree
- W.E. Moerner, Stanford — Nobel Laureate
- Priscilla Chan, co-founder & co-CEO, Chan Zuckerberg Initiative
- Luminary Honoree: Serge Saxonov, 10x Genomics
Fireside Chat
- Moderator: Christina Curtis, Stanford
- W.E. Moerner, Stanford
- Priscilla Chan, Chan Zuckerberg Initiative
Fireside chat with Serge Saxonov, 10x Genomics
Unraveling Tissue Architecture with Single-Cell & Spatial Multi-Omics
- Joakim Lundeberg, SciLifeLab
- Garry P. Nolan, Stanford
- Tae Hyun Hwang, Vanderbilt University Medical Center
Tumor Evolution & Clonal Dynamics: From Models to Monitoring
- Chair: Christina Curtis, Stanford
Multi-Omics-Driven Early Detection: Beyond Liquid Biopsy
- Ash Alizadeh, Stanford
- Alex Aravanis, Moonwalk Biosciences
Personal Omics at Scale, What Longitudinal Profiles Add to Early Detection
- Michael Snyder, Stanford
AI in Molecular Diagnostics: Integrating Multi-Omics & Clinical Data
- Chair: Marina Sirota, UCSF
- Olivier Gevaert, Stanford
- Rebecca Critchley-Thorne, Castle Biosciences
Nanomechanical Signatures for Cancer Diagnostics: Insights from Tumor Biophysics
- Chair: Marija Plodinec, Artidis
Day 3: Track 4 — Precision Aging & Precision Longevity
Integrated Precision Medicine Track
Track Chair: Alex Zhavoronkov, Insilico Medicine
PMWC Award Ceremony Honorees
- Steve Horvath, UCLA
- David Sinclair, Harvard
- Nir Barzilai, Albert Einstein College of Medicine
AI & Biomarkers for Measuring Aging
- Chair: Alex Zhavoronkov, Insilico Medicine
- Luigi Ferrucci, NIH
- Sara Hägg, Karolinska Institutet
- Steve Horvath, UCLA
Epigenetic Rejuvenation & Delivery for Clinical Translation
- Ryan (Yuancheng) Lu, Whitehead Institute / MIT
- David Sinclair, Harvard
Clinical Trial Design & Functional Endpoints for Healthspan
- Nir Barzilai, Albert Einstein
Precision Aging & Longevity Focused on Limited Lifespan Evidence, Vanishing Blue Zones, and Payer ROI
- S. Jay Olshansky, University of Illinois
Mitochondrial Function and Metabolic Interventions in Healthy Aging
Senolytics and Cellular Senescence: Translating Lab Findings to Patients
Wearable and Digital Biomarkers for Monitoring Aging Interventions
Multi-Omics Approaches to Understanding Biological Aging
Equity and Access in Aging Interventions: Avoiding Healthspan Gaps
Senolytics and Cellular Senescence: Translating Lab Findings to Patients
Wearable and Digital Biomarkers for Monitoring Aging Interventions
Multi-Omics Approaches to Understanding Biological Aging
Equity and Access in Aging Interventions: Avoiding Healthspan Gaps
- Select Speakers:
Amanda Acerbi, PharmD
Precision Medicine Global Director
Johnson & Johnson (Janssen)
“I am thrilled to hear about the impressive [2026] lineup of speakers and the engaging topics planned for the conference.”
Amanda Cashin, PhD
Life Science Company Builder & Venture Investor
Wing VC
“Congrats. This is an amazing rock star lineup.”
Tod Klingler, PHD
Founder & CEO
GeneLeap
“I’ve spoken and had exhibitions in the past at PMWC, one of my favorite conferences of the year, and this [2026] year is extra impressive.”
I-Chen Fong, PharmD
Ambulatory Care Pharmacist
Kaiser Permanente
“What an impressive lineup.”
Thomas Wilckens, MD
VP Precision Medicine; ECTT
“There is no other event, with such a lineup of leaders in their field. My annual MUST event since 2013! “
PMWC 2026 Honorees: Pioneer Award
PMWC 2026 PIONEER HONOREE, Immunotherapies & Targeted Therapies Track
PMWC 2026 PIONEER HONOREE, Immunotherapies & Targeted Therapies Track
PMWC 2026 PIONEER HONOREE, Immunotherapies & Targeted Therapies Track
PMWC 2026 PIONEER HONOREE, Therapy Guidance & Monitoring Track
PMWC 2026 PIONEER HONOREE, Integration & Implementation of Precision Medicine Track
PMWC 2026 PIONEER HONOREE, RNA, Stem Cell & Gene-Based Therapies Track
PMWC 2026 PIONEER HONOREE, Precision Aging & Longevity Track
PMWC 2026 PIONEER HONOREE, Systems Integration & Variant Interpretation Track
PMWC 2026 PIONEER HONOREE, RNA, Stem Cell & Gene-Based Therapies Track
PMWC 2026 PIONEER HONOREE NOBEL LAUREATE: Spatial Biology & Single-Cell Multi-Omics Track
PMWC 2026 PIONEER HONOREE
Co-Founder of Apple
Honorees: Luminary Award
PMWC 2026 LUMINARY HONOREE, Advances in Cell & Gene Therapies Track
PMWC 2026 LUMINARY HONOREE, Advances in Cell & Gene Therapies Track
PMWC 2026 LUMINARY HONOREE, AI & Computational Medicine Track
PMWC 2026 LUMINARY HONOREE, Systems Integration & Variant Interpretation Track
PMWC 2026 LUMINARY HONOREE, AI in Clinical Decision Support & RWE Track
PMWC 2026 LUMINARY HONOREE, Integration & Implementation of Precision Medicine Track
PMWC 2026 LUMINARY HONOREE, RNA, Stem Cell & Gene-Based Therapies Track
PMWC 2026 LUMINARY HONOREE, Precision Aging & Longevity Track
PMWC 2026 LUMINARY HONOREE, AI in Drug Discovery & Computational Medicine
PMWC 2026 LUMINARY HONOREE, Precision Aging & Longevity Track
PMWC 2026 LUMINARY HONOREE, Spatial Biology & Single-Cell Multi-Omics Track
PMWC 2026 LUMINARY HONOREE, AI in Clinical Decision Support & RWE Track
Track Chairs
Advances in Cell & Gene Therapies Track Chair
AI in Imaging & Predictive Simulation Track Chair
Liquid Biopsy – Early Detection & Screening Track Chair
Immunotherapies & Targeted Therapies Track Chair
AI in Clinical Decision Support & RWE Track Co-Chair
AI in Clinical Decision Support & RWE Track Co-Chair
Liquid Biopsy – Therapy Guidance & Monitoring Track Chair
Integration & Implementation of Precision Medicine Co-Track Chairs
RNA, Stem Cell and Gene-Based Therapies Track Chair
AI in Drug Discovery & Computational Biology Track Co-Chairs
AI in Drug Discovery & Computational Biology Track Co-Chairs
Spatial Biology & Single-Cell Multi-Omics Track Chair
