Speaker Profile
M.D., Ph.D., Chief of Stanford BMT and Cell Therapy Program, Stanford
Biography
Dr. Miklos is the Chief of Stanford BMT and Cell Therapy Program that provides 750 cancer cell therapies annually. Our BMT-CT research fosters the development of both laboratory immunologists, and clinical translational researchers. Our allogeneic hematopoietic cell transplantation (alloHCT) research is optimizing graft content of HSC, conventional T lymphocyte, and regulatory T cell content in order to cures blood cancers via beneficial graft-v-tumor (GVT) immunity while reducing GVHD risk. Our CAR-T research provides the most direct targeting of cancer and is dramatically improving leukemia and Lymphoma with no GVHD risk. Our goal is to combine graft engineered allogeneic HCT with CAR-T benefit. The Miklos lab pioneered protein microarray technologies to discover clinically relevant allogeneic antibodies. Our clinical trials established cGVHD therapeutic benefits using anti-B cell drugs rituximab and ibrutinib. More recently, our team developed human correlative assays to optimize CAR-T therapy including ctDNA MRD, flow cytometry tumor antigen quantification, Immune phenotype CAR-T characterization (CAR-FACS), and single cell RNA characterization of CAR-T cells. Immunotherapy is revolutionizing cancer treatment and Stanford Cancer Cell Therapy Program is developing and evaluating the most promising chimeric antigen T-cell (CAR-T) therapies targeting CD19, CD20, CD22, CD79A, and BCMA.
Session Abstract – PMWC 2027 Silicon Valley
Track Chair:
Cindy Perettie, Kite Pharma
PMWC Award Ceremony
• Katy Rezvani, MD Anderson (Luminary)
• David Miklos, Stanford (Luminary)
• Frederick Locke, Moffitt Cancer Center (Luminary)
Featured Speakers
• Katy Rezvani, MD Anderson
• David Miklos, Stanford
• Frederick Locke, Moffitt Cancer Center
• Arie Belldegrun, Allogene Therapeutics
• Paul Hastings, Nkarta Therapeutics
• Priti Hegde, Kite Pharma
• Andrew Scharenberg, Umoja Biopharma
• Brett Staahl, Scribe Therapeutics
• Marcela Maus, Mass General Brigham / Harvard
• Antoni Ribas, UCLA
• Saul Priceman, USC
• Sabine Heitzeneder, Stanford
Off-the-Shelf Cell Therapies
NK, iPSC, and allogeneic T cells: what wins beyond autologous CAR-T.
AI in Cell Therapy: Research to Commercialization
How AI is reshaping discovery, product design, manufacturing, and clinical translation.
The Bottleneck: Manufacturing at Scale
Capacity, automation, cost of goods, and the realities of getting engineered cells to patients.
In Vivo Delivery: The Make-or-Break Layer
Targeting the right tissue safely enough to make in vivo engineering real.
Why Cell Therapies Fail in Solid Tumors and What Works
The microenvironment, antigen escape, and programs showing real responses.
Approved to Effective
Real-world outcomes, access, and what CAR-T still gets wrong after approval.
PMWC Hall of Impact
Previous Speakers Include
Nobel laureates, technology founders, regulators, CEOs and scientific pioneers who have taken the PMWC stage.
